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Normal tissues with high metabolic activity, iron dependency, or rapid turnover, including the liver, kidneys, heart, and intestinal mucosa, are vulnerable to off-target RCDmediated tissue damage, which may cause organ dysfunction and limit clinical application (233235)

24 Compounding is a commercial activity, not a regulatory compliance exercise in the context of creating an ANDA

Off-label male use context: The doses discussed on Reddit (anastrozole 0.25 to 0.5 mg twice or three times weekly, exemestane 12.5 to 25 mg every other day or daily) are empirical, not trial-derived